Generic Name: Sertraline
Drug Form: Coated Tablet
Quantity/Volume: 56 pcs/50,100 mg
Indications:
Major Depressive Disorder (Unipolar)
Obsessive Compulsive Disorder
Panic Disorder
Post-Traumatic Stress Disorder
Premenstrual Dysphoric Disorder
Social Anxiety Disorder
Dosage and administration
Take the medicine by mouth.
Take the medicine with or without food.
Maximum daily dose: 200 mg
Children
How to take and the amount should be determined by your doctor.
If you have liver or kidney problems, consult your doctor about the dosage.
Warnings and Precautions
Before taking this medicine, consult your doctor if you have any of the following conditions:
Epilepsy or a history of seizures
Bipolar disorder or schizophrenia
Liver problems
Kidney problems
History of stroke
Heart problems
High blood pressure
Low sodium levels in blood tests
Bleeding problems
If you accidentally take more than the prescribed dose, go to the nearest medical center with the medicine blister as soon as possible.
If you miss a dose, take the medicine if it is not time for your next dose, but do not double the dose if it is time for your next dose. Take only the next dose as usual.
Sertraline can cause drowsiness or affect your ability to make decisions, think clearly, or react quickly. Therefore, avoid driving or doing things that require full attention and alertness.
Stopping medication abruptly can lead to complications, so do not stop taking the medication without consulting your doctor.
Drug Interactions
Consult your doctor if you are taking any of the following medications:
Medicines with antiplatelet properties (such as P2Y12 inhibitors, NSAIDs, SSRIs, etc.), medications with blood glucose-lowering effects, alcohol (ethyl), amphetamines, anticoagulants, antiemetics, antipsychotics, apixaban, aspirin, bupropion, buspirone, carbamazepine, cephalothin, citalopram collagenase (systemic), cyclobenzaprine, CYP3A4 inducers (moderate, strong), cyproheptadine, dabigatran etexilate, dapoxetine, darunavir, dasatinib, deoxycholic acid, desmopressin, dexmethylphenidate-methylphenidate, disulfiram, duloxetine, enoxaparin, ergot derivatives, erythromycin (systemic), fosphenytoin-phenytoin, Glucosamine, grapefruit juice, heparin, ibrutinib, lipid emulsion (fish oil-based), methadone, methylene blue, monoamine oxidase inhibitors (antidepressants), multivitamin/fluoride (with ADE), multivitamin/mineral (with ADEK), nefazodone, selective nonsteroidal anti-inflammatory drugs, nonsteroidal anti-inflammatory drugs (topical), omega-3 fatty acids, pentoxifylline, pimozide, prostacyclin analogs, QT prolonging agents (highest risk), rivaroxaban, salicylates, selegiline, thiazide and thiazide-like diuretics, thioridazine, thrombolytic agents, tipranavir, tramadol, tricyclic antidepressants, urokinase, vasopressin
Adverse effects
In addition to the desired therapeutic effects, any drug may cause some unwanted effects. Although not all of these side effects will occur in every person, seek medical attention immediately if you experience any of the following symptoms:
Severe skin rash with blistering of the mouth and tongue
Allergic reaction with symptoms such as itchy skin rash, difficulty breathing, wheezing, swelling of the eyelids, face, or lips
Restlessness, confusion, diarrhea, high temperature and blood pressure, excessive sweating, and rapid heartbeat
Yellowing of the skin and eyes
Suicidal thoughts
Seizures
Experience a manic phase (symptoms may include: extreme energy, severe sleep problems, excessive happiness, reckless behavior, talking more or faster, unusual grand ideas)
Changes in appetite or weight
Common side effects
Diarrhea, nausea, dry mouth, dizziness, drowsiness, fatigue, insomnia, edema, high blood pressure, palpitations, syncope, tachycardia, vasodilation, alopecia, dermatitis, excessive sweating, rash Erythematous rash, decreased libido, diabetes, galactorrhea not related to labor, high blood cholesterol, hypoglycemia, hypothyroidism, weight loss, abdominal pain, bruxism, constipation, decreased appetite, indigestion, increased appetite, vomiting, ejaculation disorder, erectile dysfunction, hematuria, priapism, sexual dysfunction, urinary incontinence, vaginal bleeding, rectal bleeding, increased liver enzymes, anaphylaxis, abnormal gait, restlessness, anxiety, ataxia, coma, confusion, euphoria, hallucinations, impaired consciousness, irritability, lethargy, psychomotor agitation, convulsions, yawning, excessive muscle activity, muscle spasms, visual disturbances, tinnitus, bronchospasm.
Other side effects
Aggressive behavior, joint pain, muscle contraction, nosebleed, fever
Contraindications
Avoid taking sertraline in the following cases:
History of allergy to sertraline or any of the product’s excipients
Use of MAO inhibitors, including intravenous linezolid and methylene blue, or within 14 days of stopping use
Use of pimozide, disulfiram, selegiline, dapoxetine.
Pregnancy and lactation
The use of the drug during pregnancy and lactation is permitted only when the need for it is clearly established and the benefits outweigh the possible harm to the fetus, and during lactation, it is prescribed by a specialist physician.
Storage:
Keep the drug out of the sight and reach of children.
Avoid using expired drugs.
Store the drug at a temperature below 30 degrees, away from light and moisture.